Strategic Direction Through Thematic Alignment

Guided by an evolving list of priority research questions originally assembled in 2018, the AD Data Initiative is shaping the future of scientific discovery by integrating insights from our Advisory Board, community feedback, and thought leadership engagements. We envision this list of questions as a dynamic blueprint that will drive innovation, inform strategic decisions, and inspire the next generation of collaborative breakthroughs.

Mapping Priority Research Questions to 8 Key Themes

Biological pathways and trials
Cognitive function measures
Disease progression tracking
Novel biomarkers and diagnostics
Prevention
Subtypes
Risk prediction in low- and middle-income countries (LMICs)
Risk factors for Amyloid-Related Imaging Abnormalities (ARIA)

Cross-cutting themes include 

  • Diversity of study participants 
  • Generative AI to accelerate progress

Strategic levers to accelerate progress 

Gates Sr AD Fellows

Data Challenges

Research Collaborations & Consortia 

Drivers Projects