Scientific Driver Projects
Dedicated global teams answering the field's priority research questions — bringing together the right scientists and the right data to move each one forward.
What is a Driver Project?
Driver Projects stand up dedicated, global, multidisciplinary teams to answer the field’s priority research questions.
Each one brings together the right scientists and the right data — including unpublished datasets unlocked for researcher access — to move a specific question forward.
The goal is practical: better early detection and diagnosis, sharper risk stratification, and stronger treatment, intervention and clinical-trial design.
What Sets a Driver Project apart?
Priority question
A focused research question, not a broad theme.
Global consortium
A dedicated, multidisciplinary team spanning institutions and geographies.
Unlocked data
Relevant datasets identified — and opened — for researcher access.
Funding & advisory
Dedicated funding and a technical advisory group to guide the work.
The Four Driver Projects
Heterogeneity & Subtypes | GNPC
Uncovering subtypes of Alzheimer's and related dementias from proteomic and phenotypic data to enable more accurate diagnosis and better-matched treatment.
Sex & Gender Differences | S|GN
Coordinating a global effort to integrate sex and gender into ADRD research — for more precise prevention, diagnosis and treatment.
Disease Progression Tracking | Rates of Progression
Modeling harmonized trial and cohort data to uncover the factors that drive how fast disease progresses — and how to act on them.
Biological Pathways & Trials | BACE Inhibitors
Reanalyzing harmonized BACE inhibitor trial data to understand cognitive decline and reassess the path to safer, earlier prevention.