What is a Driver Project?
Driver Projects stand up dedicated, global, multidisciplinary teams to answer the field's priority research questions. Each one brings together the right scientists and the right data — including unpublished datasets unlocked for researcher access — to move a specific question forward.
The goal is practical: enable better early detection and diagnosis, sharper risk stratification, and stronger treatment, intervention and clinical trial design.
What sets one apart
A focused priority research question, not a broad theme
A dedicated global, multidisciplinary consortium
Relevant data identified — and unlocked — for researcher access
Dedicated funding and a technical advisory group to guide the work
The Four Driver Projects
GNPC
Uncovering subtypes of Alzheimer's and related dementias from proteomic and phenotypic data to enable more accurate diagnosis and better-matched treatment.
S|GN
Coordinating a global effort to integrate sex and gender into ADRD research — for more precise prevention, diagnosis and treatment.
Rates of Progression
Modeling harmonized trial and cohort data to uncover the factors that drive how fast disease progresses — and how to act on them.
BACE Inhibitors
Reanalyzing harmonized BACE inhibitor trial data to understand cognitive decline and reassess the path to safer, earlier prevention.